Download An Introduction to Molecular Biotechnology- Fundamentals, by Michael Wink PDF

By Michael Wink

Molecular biotechnology maintains to triumph, as this textbook testifies - edited by way of one of many educational pioneers within the box and written by way of skilled pros. This thoroughly revised moment variation covers the whole spectrum, from the basics of molecular and cellphone biology, through an outline of normal equipment and applied sciences, the applying of some of the "-omics", and the improvement of novel drug pursuits, correct as much as the importance of process biology in biotechnology. the full is rounded off through an creation to commercial biotechnology in addition to chapters on corporation starting place, patent legislation and advertising.
the hot version features:
- huge structure and whole colour throughout
- confirmed constitution in keeping with fundamentals, equipment, major subject matters and fiscal perspectives
- New sections on approach biology, RNA interference, microscopic innovations, excessive throughput sequencing, laser functions, biocatalysis, present biomedical purposes and drug approval
- Optimized educating with studying pursuits, a word list containing round 800 entries, over 500 vital abbreviations and extra reading.
the one source when you are heavily drawn to the topic.

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Additional info for An Introduction to Molecular Biotechnology- Fundamentals, Methods and Applications

Example text

1 D). This results in many free ends on which the enzyme glycogen phosphorylase can begin degradation simultaneously. 1 Structure and Function of Sugars Fig. 1 Composition and structure of sugar molecules. (A) Structures of the most important aldoses and ketoses. (B) Ring structures of pentoses and hexoses (hemiacetal and hemiketal formations); important isomers of glucose. (C) Important derivatives of glucose and galactose. (D) Formation of disaccharides and polysaccharides (starch (amylose), amylopectin, glycogen, cellulose).

Functional groups on the side chains do not take part in these structural elements. 11 describes the structure of helices and pleated sheets more precisely. Other structures include loops and random coils. A b-sheet structure element is often found at the inner core of many proteins. The b-pleated sheet can appear between neighboring polypeptide chains that have the same orientation (parallel chain). When a polypeptide chain folds back on itself and is aligned in parallel, the chains are termed antiparallel chains.

Interactions that occur between antigens and antibodies (see Chapter 28), between ligands and hormone receptors as well as between enzymes and their substrates are particularly intimate and selective. The topic of protein–protein interactions is discussed further in Chapter 24. Most of the cellular building blocks are inert molecules that are not prone to react chemically. Significant activation energy has to be overcome in order to start an energy-consuming chemical reaction. In the laboratory this can be achieved by heating and adding acids or bases.

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